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The Serengeti Rules: The Quest to Discover How Life Works and Why It Matters - Sean B Carroll [epub]

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Description

 							
  
  Published
2016
  
  How does life work? How does nature produce the right numbers of zebras and lions on the African
savanna, or fish in the ocean? How do our bodies produce the right numbers of cells in our organs and bloodstream? In
The Serengeti Rules, award-winning biologist and author Sean Carroll tells the stories of the pioneering scientists who
sought the answers to such simple yet profoundly important questions, and shows how their discoveries matter for our
health and the health of the planet we depend upon.
  
  One of the most important revelations about the
natural world is that everything is regulated—there are rules that regulate the amount of every molecule in our
bodies and rules that govern the numbers of every animal and plant in the wild. And the most surprising revelation about
the rules that regulate life at such different scales is that they are remarkably similar—there is a common
underlying logic of life. Carroll recounts how our deep knowledge of the rules and logic of the human body has spurred
the advent of revolutionary life-saving medicines, and makes the compelling case that it is now time to use the
Serengeti Rules to heal our ailing planet.
  
  A bold and inspiring synthesis by one of our most accomplished
biologists and gifted storytellers, The Serengeti Rules is the first book to illuminate how life works at vastly
different scales. Read it and you will never look at the world the same way again.
  
  **
  
 
Review
  
  "In this remarkably engaging book, Carroll . . . persuasively argues that life at all levels of
complexity is self-regulated, from the inner workings of cells to the larger relationships governing the Serengeti
ecosystem. . . . Carroll superbly animates biological principles while providing important insights."--*Publishers
Weekly*
  
  "A thought-provoking challenge to complacency."--*Kirkus*
  
  "Carroll's book is
fantastic, a success story in going form the specific to the general. It helps that Carroll is a gifted writer,
captivating and thoughtful, and highly respectful of the reader. Carroll brings in the history of thought and research
in the relevant areas of physiology, ecology etc. His messages are framed in the larger context of the Earth's overall
health and important environmental issues. He links the subject matter to key central themes in biological theory (such
as natural selection and evolution). And this is all done very well. You've seen the synthetic overviews of life and
evolution framed in chaos theory, complexity theory, even quantum physics. This is better. This is a book to give to
your favorite biology teacher (high school or college), and that teacher will take from it examples, connections,
lessons, ways of telling, that will enrich their teaching immeasurably."--Greg Laden, ScienceBlog's Greg Laden
 

  "[A]s a subject for popular science, regulation seems to fail the thrill test; genetics and neuroscience appear
more alluring. Now Sean B. Carroll. . . . Has risen to the challenge with this wonderful book about the natural control
of numbers in living systems. Carroll is one of the top storytellers in contemporary science, as his previous writings
about evolutionary biology have shown. Here he uses his narrative skills to take us on a scientific journey through time
and space--making his case through the work of researchers around the world who have built up rules of life over the
past century. . . . [The Serengeti Rules] is wholeheartedly recommended for its entertaining view of biology from an
original perspective."--Clive Cookson, *Financial Times*
  
  "[A] deep journey into the rules of life on
Earth. . . . By introducing us to the great pioneers of molecular biology, like Jacques Monod (enzyme regulation), Akira
Endo (lovastatin developer) and Janet Rowley (cancer and inheritance of genetic diseases), Carroll sets the reader up
with a strong foundation in the natural processes that go on within our own bodies, and describes how breakthroughs
happen, such as the discovery of 'repressors' and 'suppressors,' (which act, not by 'doing things,' but by preventing
things), and double-negative regulatory logic. We also learn what happens when these mechanisms fail."--Cathy Taibbi,
Examiner.com
  
  From the Back Cover
  
  "A master storyteller, Carroll explores the unity of
biology from the molecular level to the Serengeti, the rules that regulate life, and the consequences when regulation
breaks down. A fascinating journey from beginning to end, this book will educate and entertain readers at all levels and
leave them with a better understanding of how the biosphere works."--Simon Levin, Princeton University, author of
*Fragile Dominion: Complexity and the Commons*
  
  "The Serengeti Rules is a superb journey of a book written
by a scientist of the first rank. Unfolding seamlessly from molecule to ecosystem, it explains with authority and grace
why modern biology is central not just to human life but to that of the planet itself."--Edward O. Wilson, Harvard
University
  
  "As one of our leading biologists and communicators, Sean Carroll has merged a passion for
scientific discovery with a flair for telling great stories of exploration. In The Serengeti Rules, Carroll has crafted
a work of epic sweep that travels the globe in search of the logical rules that govern all of life, from tiny molecules
to entire ecosystems. The Serengeti Rules both delights and enlightens--I was left marveling at the human achievement
behind scientific breakthroughs and the sheer beauty of the working of living systems."--Neil Shubin, author of *Your
Inner Fish: A Journey into the 3.5-Billion-Year History of the Human Body*
  
  "Original, provocative, and
beautifully crafted, Carroll's book provides a glimpse into the deeper laws of biology that govern the earth. With his
inimitable style of storytelling combined with a deep knowledge of science, Carroll takes us on a rollicking adventure,
reminding us that the rules that apply to ecosystems also apply to the human body. This book is a must-read for anyone
who cares about the future of the planet."--Siddhartha Mukherjee, author of *The Emperor of All Maladies: A Biography of
Cancer*
  
  "This is a rattling good read by one of the leading scientists of our time. The Serengeti Rules
made me think differently about what we biologists do. This is a book that needs to be shouted from the
rooftops."--Andrew F. Read, Pennsylvania State University
  
  "Masterful and compelling. The Serengeti Rules
is a significant contribution, one that will be welcomed by professional biologists and a wide range of lay
readers."--Harry W. Greene, author of *Tracks and Shadows: Field Biology as Art* 						

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